Experimental Models in Syrian Golden Hamster Replicate Human Acute Pancreatitis
نویسندگان
چکیده
منابع مشابه
Experimental Models in Syrian Golden Hamster Replicate Human Acute Pancreatitis
The hamster has been shown to share a variety of metabolic similarities with humans. To replicate human acute pancreatitis with hamsters, we comparatively studied the efficacy of common methods, such as the peritoneal injections of caerulein, L-arginine, the retrograde infusion of sodium taurocholate, and another novel model with concomitant administration of ethanol and fatty acid. The severit...
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This Article contains typographical errors in the Discussion section. " Our previous study 8 had proven that the local high concentration of free fatty acids in hypertriglyceridemic mice resulted in increased susceptibility to acute pancreatitis. We also had found enhanced susceptibility to acute pancreatitis in hypertriglyceridemic Syrian golden hamsters 26. " should read: " Our previous study...
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Of a series of ninety-six young male Syrian Golden hamsters, 13% developed lethargy, anorexia, diarrhoea and colocolic intussusception when their diet was changed from a basal laboratory-grade rodent chow to a nutritionally complete semi-purified diet. Histologically, the colon of the hamsters with intussusception had markedly reduced mucus production. Plasma levels of gastric inhibitory polype...
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17rethan in the drinking water (0.~2-0.4 per cent) was administered to 5to 7-weekold Syrian golden hamsters and continued for 4~ weeks with an 8-week interval between the 40th and 48th week. This t rea tment has been found to give rise to melanotic tumors of the skin, papillomas and carcinomas of the forestomach, adenomatous polyps of the cecum, pulmonary adenomatosis, m a m m a r y tumors, hep...
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The carcinogens 9,10-dime thy 1-1,2-benzanthracene, 20-methylcholanthrene, 3,4benzpyrene, 1,2,5,6-dibenzanthracene, 1,2-benzanthracene, and 2-anthramine have been tested topically in the Syrian golden hamster. The mouse skin tumor-promoting agents, croton oil and polyoxyethylene sorbitan monostearate (Tween 60), have been tested on hamster skin following a single applica tion of 9,10-dimethyl-l...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep28014